Factory-Direct Clotting Factor Plasma Reagent Test Kits: Accurate And Reliable Results

Coagulation Solution
Series	Product Name	Abbr
Clotting Factor Plasma Reagent	Clotting Factor II-Deficient Plasma	F II
	Clotting FactorV-Deficient Plasma	F V
	Clotting Factor VII -Deficient Plasma	F VII
	Clotting Factor X-Deficient Plasma	F X
	Clotting Factor VIII -Deficient Plasma	F VIII
	Clotting Factor IX-Deficient Plasma	F IX
	Clotting Factor XI-Deficient Plasma	F XI
	Clotting Factor XII-Deficient Plasma	F XII
	Berichrom FXIII	F XIII

Most clotting factors were initially discovered as agents functionally defcient in the plasmas of rare patients with hereditary coagulation disorders. During 1940s to 1960s, many factors were named by diferent investigators after the name of the patient who lacked a new factor. There are different clotting factors present in blood, carries the clotting cascade andexcessive bleeding may cause a deficiency in the clotting. Coagulation factors are designated by Roman numerals as follows: Factor XII, Factor XI, Factor IX, Factor VIII, Factor X, Factor V and Factor II Factor VII and FXIII. Activated clotting factors are designated with a suffix“a,” e.g., FVIIIa, FIXa.Coagulation factors are all produced in the liver hepatocytes. The detection of coagulation factors can now be achieved with plasma fibrinogen (FIB) content determination, plasma factor VIII, IX, XI and XII procoagulant activity assay, plasma factor II, V, VII and X procoagulant activity assay, plasma factor Factor XIII Qualitative Test and Plasma Factor XIII Subunit Antigen Determination. Inherited coagulation factor deficiency disorders.It is characterized by frequent bleeding symptoms since childhood, and a family history of inheritance.Except for hemophilia A and B, which are sex chromosomal recessive inheritance, they are generally autosomal recessive inheritance. Both men and women can be affected, and there is often a history of consanguineous marriage. The diseases in this group are all single coagulation factor deficiency, of which factor VIII deficiency (hemophilia A) is the most common, and all other factors except III and IV can be deficient Acquired coagulation factor deficiency disease. All of them are multi-factor deficiency and have primary diseases. Common ones such as vitamin K deficiency are factor II, VII, IX, and X deficiency, as well as severe liver disease.Diagnosis is by examining coagulation patterns and correcting tests. Treatment with fresh plasma or cryoprecipitate is effective, and for acquired patients, the primary disease should be treated Most studies believe that the activity of coagulation factor II is normal or slightly decreased in patients with acute hepatitis and mild chronic hepatitis; in patients with moderate, severe chronic hepatitis and cirrhosis, the activity level of coagulation factor II is significantly decreased, indicating that the degree of its reduction is related to liver cells. The activity of coagulation factor V is only reduced when liver function is decompensated or severe liver disease, so it is considered to be a good indicator for judging the prognosis of patients with liver disease. Coagulation factor VII has the shortest half-life (4~6h), and the plasma content is low (0.5~2mg/L), so it can be used as an early diagnostic indicator of protein synthesis dysfunction in patients with liver disease.

Clotting Factor Plasma Reagent Test Kit

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