Glycometabolism Chemiluminescence Immunoassay Kit - Factory Direct Pricing & Quality Assured

Chemiluminescent Solution（General Items）
Series	Product Name	Product Name
Glycometabolism	C-peptide	CP
Glycometabolism	Insulin	INS

C-peptide (CP) is a polypeptide with 31 amino acids (AA33-63) and a molecular weight of about 3021 Daltons. C-peptide is secreted by pancreatic beta cells, and it shares a common precursor with insulin, proinsulin. Proinsulin is split into 1 molecule of insulin and 1 molecule of C-peptide, so C-peptide is the same molar amount as its own insulin. Since C-peptide is not easily degraded by the liver, the content of C-peptide reflects the content of insulin, which can accurately reflect the function of islet cells. At the same time of oral glucose tolerance test, blood can be drawn to measure serum C-peptide levels 1 hour, 2 hours, and 3 hours after fasting blood glucose load. In normal people, the level of C-peptide increased to 3 times the basal level 60 minutes after taking glucose. above. Type 1 diabetes C-peptide levels are extremely low, and the postprandial C-peptide rise in patients with islet dysfunction is often less than 3-fold. For patients receiving insulin therapy, due to the generally high concentration of endogenous anti-insulin antibodies, measuring insulin levels in blood cannot evaluate the function of their own pancreatic islets. The C-peptide level can be measured to evaluate the function of their own pancreatic β-cells. Measuring C-peptide may Contributes to the assessment of residual β-cell function in the early stage of type 1 diabetes, and the diagnosis of autoimmune diabetes in adults (LADA) and type 2 diabetes. Insulin (INS) is secreted by pancreatic beta cells within the pancreatic islets. Insulin is the only hormone in the body that lowers blood sugar and the only hormone that simultaneously promotes the synthesis of glycogen, fat, and protein. The mechanism of action belongs to the receptor tyrosine kinase mechanism. Insulin can promote the uptake and utilization of glucose by tissue cells throughout the body, and inhibit the decomposition of glycogen and gluconeogenesis. When the glucose level returns to the baseline, the insulin level also returns to the baseline. Insufficient insulin secretion is the main cause of elevated blood sugar and diabetes. Clinically, it is mainly used for the pathophysiology of diabetes and the evaluation of pancreatic β-cell function, the differential diagnosis of insulin-dependent diabetes mellitus and non-insulin-dependent diabetes mellitus, and the etiological evaluation of fasting hypoglycemia and certain insulinemia. One of the major clinical applications of insulin is in the diagnosis and management of diabetes mellitus, which is caused by insufficient tissue uptake of glucose, resulting in chronic hyperglycemia. Diabetes has serious complications such as kidney failure, heart disease, nerve damage, blindness and gangrene. Severe episodes of hyperglycemia can trigger ketoacidosis and coma.

Glycometabolism Chemiluminescense Immunoassay Kit

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