Torch Chemiluminescense Immunoassay Kit

The use of some assays has become particularly important after implementation of screening programs in a number of countries to identify pregnant women at risk of materno-fetal infections caused by Toxoplasma, Rubella, Cytomegalovirus and Herpes simplex viruses and to monitor the outcome once one disease is recognized.

Products Details

Chemiluminescent Solution(General Items)

Series

Product Name

Product Name

Torch

Toxoplasma IgG

Toxo IgG

Toxoplasma IgM

Toxo IgM

Rubella Virus IgG

RV-IgG

Rubella Virus IgM

RV-IgM

Cytomegalovirus IgG

CMV IgG

Cytomegalovirus IgM

CMV IgM

Herpes Simplex Virus I IgG

HSV-Ⅰ-IgG

Herpes Simplex Virus I IgM

HSV-Ⅰ-IgM

Herpes Simplex Virus Ⅱ IgG

HSV-Ⅱ-IgG

Herpes Simplex Virus Ⅱ IgM

HSV-Ⅱ-IgM

The use of some assays has become particularly important after implementation of screening programs in a number of countries to identify pregnant women at risk of materno-fetal infections caused by Toxoplasma, Rubella, Cytomegalovirus and Herpes simplex viruses and to monitor the outcome once one disease is recognized. 1.Toxoplasma gondii (Toxoplasma gondii) is a widespread intracellular protozoa that can damage a variety of organs and tissues. The main route of infection is contact with cats, dogs or other animals infected with Toxoplasma gondii and consumption of contaminated raw eggs, raw milk, raw meat, etc. Toxoplasmosis (toxoplasmosis), also known as toxoplasmosis, is mostly recessive infection or subclinical in humans. After human infection with Toxoplasma gondii, antibodies appear in serum, which can be determined by detecting IgM and IgG antibodies in serum. Generally, IgM antibodies are produced first, followed by IgG antibodies. The titer of IgM antibody gradually decreased to a lower level soon after reaching the peak, while the IgG antibody basically stabilized at a higher titer after reaching the peak, and lasted for a long time. IgG antibody is a good indicator for diagnosing primary infection, active infection and even intrauterine infection caused by Toxoplasma gondii infection in pregnant women. 2.Rubella virus (RV) is the causative agent of rubella. The virus spreads through the respiratory tract, and after the proliferation of regional lymph nodes, it spreads throughout the body through viremia. The most serious problem of rubella virus infection is vertical transmission and congenital infection of the fetus. Pregnant women infected with rubella virus are extremely harmful to the fetus, which can lead to miscarriage or stillbirth. The virus can also cause congenital rubella syndrome, which is mainly due to congenital defects in infants, and manifests as congenital deafness, congenital heart disease, cataract and other malformations after birth, as well as other rubella syndromes, such as hepatomegaly, jaundice hepatitis, meningitis , pneumonia, etc. 3.Cytomegalovirus (CMV) is an opportunistic pathogenic virus that is ubiquitous in nature and is quite common in the general population. In addition to infecting human fibroblasts, human cytomegalovirus can also infect endothelial cells and macrophages, causing cytomegalovirus infection, hepatitis, retinitis and other diseases. In addition, human cytomegalovirus infection is more serious in pregnant women and children, which is an important factor in causing birth defects and various irreversible damages. Once a person is infected with cytomegalovirus, it will be carried for life. When the latent virus is activated by a certain incentive, it can cause obvious clinical symptoms. 4.Herpes simplex virus is a common pathogen that seriously endangers human health and causes skin diseases and venereal diseases. Human herpes simplex virus exists in two serotypes: HSV-1 and HSV-2. HSV-1 mainly caused infections above the waist, and the most common infection sites were the mouth and lips; HSV-2 mainly caused infections below the waist. HSV-1 can cause not only primary infection, but also latent infection and recurrence. Primary infections most commonly cause herpetic keratoconjunctivitis, oropharyngeal herpes, skin herpetic eczema, and encephalitis. The latent sites are the superior cervical ganglion and the trigeminal ganglion. HSV-2 is mainly spread through direct close and sexual contact. The latent site of the virus is the sacral ganglia, and the latent virus can be activated after stimulation, causing recurrent infection.

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