Factory Direct ALD Test Kit - Accurate Autoimmune Liver Disease Diagnosis

Chemiluminescent Solution（Autoimmune Diseases）
Series	Product Name	Abbr
Autoimmune Encephalitis Antibodies Profile	Anti-NMDAR Antibody	NMDAR
	Anti-AMPA1 Antibody	AMPA1
	Anti-AMPA2 Antibody	AMPA2
	Anti-LGI1 Antibody	LGI1
	Anti-CASPR2 Antibody	CASPR2
	Anti-GABARB Antibody	GABABR
	Anti-IgLON5 Antibody	IgLON5
	Anti-DPPX Antibody	DPPX

NMDAR is a subtype of ionotropic glutamate receptor and its molecular structure is complex. The mainly clinical manifestations are psychiatric and behavioral abnormalities, seizures, and near event memory impairment and other multifocal or diffuse brain damage. AMPA receptors mediate fast excitatory synaptic transmission in the central nervous system (CNS) and are involved in regulating learning and memory activity. Anti AMPAR encephalitis occurs with typical limbic encephalitis manifestations including subacute unconsciousness, depression, irritability, near memory loss and seizures with medial temporal lobe dysfunction, but generally without clinical manifestations of progressive movement disorder, central hypoventilation and autonomic dysfunction. LGI1 is a secreted protein interacting with two kinds of epilepsy related proteins CASPR2 is a member of the axon protein superfamily. Patients with positive anti CASPR2 antibody in serum or CSF can present with encephalitis, peripheral nerve hyperexcitability or Morvan’s syndrome. GABABR belongs to G protein coupled receptor, widely distributed in the brain and spinal cord, especially in hippocampus, thalamus and cerebellum. Patients can present with typical limbic encephalitis with early predominant seizures, as well as memory and behavioural abnormalities that can be very easily misdiagnosed as viral encephalitis. DPPX related encephalitis is a relatively rare AE in the clinic, which has an insidious onset and mostly a chronic course. The later clinical manifestations are diverse and lack specificity, such as CNS hyperexcitability, sensory disturbance, autonomic dysfunction, psychopsychiatric disturbance and cognitive dysfunction, and a small proportion of patients present with weakness and pain in both lower limbs with falls. C-luminary is a leading Autoimmune Encephalitis Antibodies Profile testing solutions provider, by utilizing the latest chemiluminese technology, that offers a good sensitivity, large linear range, and great stability,Quantitive testing available for some of the crucial test items.

Autoimmune Liver Disease(ALD) Test Kit

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