Factory Direct: Infectious Diseases Chemiluminescense Immunoassay Kit

Chemiluminescent Solution（General Items）
Series	Product Name	Product Name
Infectious Diseases	Hepatitis B Surface Antigen	HBsAg
	Hepatitis B Surface Antibody	HBsAb
	Hepatitis B E Antigen	HBeAg
	Hepatitis B EAntibody	HBeAb
	Hepatitis B core Antibody	HBcAb
	Treponema Pallidum	TP
	Hepatitis C Virus	HCV
	Human Immunodeficiency Virus	HIV

Hepatitis B virus (HBV) serological markers include HBsAg, anti-HBs, HBeAg, anti-HBe, anti-HBc and anti-HBc-IgM. HBsAg positive means HBV infection; anti-HBs is a protective antibody, its positive means immunity to HBV, can be seen in hepatitis B recovery and hepatitis B vaccine; HBsAg turnd negative and meanwhile anti-HBs turnd positive,is called as HBsAg serum seroconversion; HBeAg turnd negative and meanwhile anti-HBe turnd positive, is called HBeAg seroconversion; anti-HBc-IgM positive indicates HBV replication,This Phenomenon is more common in the acute phase of hepatitis B, but also in acute exacerbation of chronic hepatitis B;The total antibody of HBc is mainly anti-HBc-IgG. As long as you have been infected with HBV, this antibody is mostly positive regardless of whether the virus is cleared or not. Syphilis is caused by Treponema pallidum, a subspecies of the intracellular Gram-negative Treponema bacterium Treponema pallidum (TP). Syphilis is primarily transmitted sexually, but it can also be transmitted from mother to child during pregnancy or childbirth. Syphilis infection is divided into early (infectious) and late (non-infectious). Early syphilis can be further divided into primary syphilis, secondary syphilis and early latent syphilis. The signs and symptoms of syphilis are varied，Therefore, serological diagnosis of syphilis is important. The immune response to Treponema pallidum is a major factor in the development of lesions. The antibody response is not only directed against Treponema pallidum-specific antigens (Treponema pallidum antibodies), but also against Treponema pallidum non-specific antigens (non-Treponema pallidum antibodies); for example, antigens are released during cellular damage caused by the organism. Therefore, non-Treponema pallidum and Treponema pallidum testing are required when diagnosing syphilis. The non-Treponema pallidum test uses an antigen composed of lecithin, cholesterol, and purified phospholipids to detect antibodies against cardiolipin, which is present in many people with syphilis. The Treponema pallidum test is directed against antibodies to the Treponema pallidum protein. A positive Treponema pallidum antibody test result indicates previous exposure to syphilis. Non-Treponema pallidum tests can be effectively used to monitor disease progression and treatment responsiveness. Both of these tests are necessary diagnostic aids. The presence of HCV antibodies indicates that an individual may have been infected with HCV and may transmit HCV. HCV is a member of the Flaviviridae family and has a single-stranded positive-stranded RNA genome. Currently more than 67 subtypes have been identified and classified into 7 genotypes . Due to the high rate of asymptomatic infection, clinical diagnosis is difficult and screening tests are very important. Infection with HCV can lead to acute and chronic hepatitis disease. About 70-85% of HCV infections develop chronic disease, although this varies among patients by gender, age, ethnicity, and immune status. Chronic HCV infection may lead to cirrhosis and hepatocellular carcinoma, therefore, early anti-HCV detection is the first step in chronic hepatitis treatment to select patients who need treatment. HCV infection can be detected by HCV RNA, alanine aminotransferase (ALT), and HCV-specific immunoglobulin (anti-HCV) samples in patient serum or plasma. This can also indicate whether the infection is acute or chronic. Anti-HCV antibody tests are used alone or in combination with other tests (such as HCV RNA) to detect HCV infection and to identify blood and blood products from people with HCV infection. Human immunodeficiency virus (HIV), the causative agent of acquired immunodeficiency syndrome (AIDS), belongs to the retrovirus family.In newly infected patients, HIV p24 antigen can be seen as early as 2-3 weeks after infection. Anti-HIV antibodies can be detected in serum approximately 4 weeks after infection. Combining detection of p24 antigen and anti-HIV antibodies with a fourth-generation HIV screening assay can improve sensitivity and therefore shorten the diagnostic window compared to traditional anti-HIV assays.

Infectious Diseases Chemiluminescense Immunoassay Kit

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