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Coagulation Solution
Series	Product Name	Abbr
Screening Tests	Prothrombin Time	PT
	Activated Partial Thromboplastin Time	APTT
	Fibrinogen	Fib
	Thrombin Time	TT

Coagulation is a common test that is important to identify the patient's physical condition and is necessary before surgery. In addition, four clotting procedures are required before oral anticoagulants are required for certain diseases. The detection of four coagulation indexes plays a very important role. The examination results can timely understand whether the patient has a certain hemostatic dysfunction, so as to formulate all possible emergency measures before surgery, which has a role in the prevention and control of intraoperative hemorrhage Prothrombin Time: Prothrombin time is a screening test for detecting exogenous coagulation factors. It is used to confirm the presence of defects or inhibitors of congenital or acquired fibrinogen, prothrombin, and coagulation factors ⅴ, ⅶ, ⅹ. It is also used to monitor the dosage of oral anticoagulants, and is the preferred indicator for monitoring oral anticoagulants Thrombin Time： thrombin time measurement Prolonged thrombin time is seen in increased heparin or the presence of heparin-like anticoagulants, such as SLE, liver disease, nephropathy, etc., low (no) fibrinemia, abnormal fibrinogen, increased fibrinogen degradation products (FDP), such as DIC, primary fibrinolysis. Activated Partial Thromboplastin Time： is a screening test for examination of endogenous coagulation factors. It is used to confirm defects of congenital or acquired coagulation factors ⅷ, ⅸ or the presence of their corresponding inhibitors. It can also be used to determine deficiency of coagulation factor , prokinin releasing enzyme and high molecular weight prokinin releasing enzyme. Due to the high sensitivity of APTT and the endogenous coagulation pathway of heparin, APTT is the preferred indicator for monitoring common heparin. Fibrinogen: fibrinogen coagulation factor Ⅰ, is the main protein in the clotting process, FIB increased stress reaction in addition to physiological conditions and late pregnancy, mainly appear in the acute infection, burns, atherosclerosis, and acute myocardial infarction (mi), autoimmune diseases, multiple myeloma, acute nephritis, diabetes, pih and uremia, and so on, The decrease of FIB was mainly observed during DIC, primary hyperlytic, severe hepatitis, gangue hardening and thrombolytic therapy. Simultaneous detection of prothrombin time, activated partial thrombin time and fibrinogen has been clinically used to screen whether the coagulation mechanism of patients is normal, especially the preoperative examination of patients' coagulation function in cardiothoracic surgery, orthopedics, obstetrics and gynecology is particularly important.

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